Explore the fascinating world of SkfB, a bacterial enzyme that crafts the sporulation killing factor (SKF) using radical chemistry. Discover its modular structure, iron-sulfur clusters, and role in microbial cannibalism.Keywords: SkfB enzyme, AdoMet radical sactisynthase, bacterial sporulation, iron-sulfur clusters, structural biology
Discover how titanocene(III) catalysts enable efficient synthesis of seven-membered carbocycles in terpenoids through 7-endo radical cyclizations, bridging chemistry and biology.
Explore the groundbreaking discoveries and interdisciplinary collaborations from the 5th Brazilian Conference on Natural Products and the 31st RESEM, where science met biodiversity preservation.
Discover how scientists transform spent oyster mushroom substrate into eco-friendly ZnO/CuO nanoparticles, unlocking their potential to fight cancer and oxidative stress.
Explore the fascinating world of clavulanic acid—a natural beta-lactamase inhibitor that revolutionized antibiotic therapy. Learn how its unique structure, microbial biosynthesis, and clinical applications combat drug-resistant bacteria.
Explore the science behind celastrol, a potent triterpenoid from traditional Chinese medicine, and its groundbreaking applications in treating obesity, cancer, and neurodegenerative diseases.
Explore the hidden world of non-canonical terpene synthases—enzymes that defy traditional classifications to craft nature’s most complex molecules. Discover their revolutionary role in drug discovery, biofuels, and beyond.Keywords: Non-canonical terpene synthases, enzyme evolution, natural products, genome mining, synthetic biology
Explore how metabolic engineering is transforming styrene production from polluting petrochemical processes to eco-friendly microbial biosynthesis, unlocking cleaner plastics and greener chemistry.
Explore the world of pyrazolopyridines—their unique structures, groundbreaking applications in cancer therapy and neurology, and cutting-edge synthesis methods. Discover why these molecules are the future of drug design.
Explore the cutting-edge discoveries in chlorophyll biosynthesis, molecular engineering, and revolutionary applications in energy, medicine, and biomimicry.
Explore the chemistry, biosynthesis, and groundbreaking history of penicillin and cephalosporins—antibiotics that revolutionized healthcare and continue to combat bacterial infections today.
Discover how Trichoderma arundinaceum crafts harzianum A, a natural antifungal compound, through a two-step enzymatic dance—and why this discovery could revolutionize agriculture and medicine.